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Name | Abul Bashar Mir Md. Khademul Islam |
Designation | Professor | |
Last Degree | PhD | |
Thesis
Areas of Expertise
High-throughput biology including Whole Genome Sequencing (WGS), ChIP-seq, RNA-seq, Single Cell RNAseq (scRNA-seq), ATAC-seq HiC, microarray, Chip-on-chip, ChIP-tiling array, metagenomics.
Laboratory Skills
Microbiological techniques, cell culture, Immunoblotting/Western blotting, Immune precipitation (IP), Electrophoretic Mobility Shift Assay (EMSA), Cell transfection, cell immune staining, DAPI, Laser confocal microscopy, Fluorescent microscopy, Flow-cytometry, FACS (Fluorescence-activated cell sorter), Real time PCR, Gel electrophoresis, UV-Vis spectroscopy, Gel Immunodiffusion, Hemagglutination, Ribotyping, enzyme assay, plasmid profiling, FISH, ELISA. DNA/Plasmid extraction, cloning etc. High-throughput techniques: microarray, ChIP-seq, RNA-seq.
Computer OS and Programming/Scripting Skills
Unix/Linux; shell/bash/awk scripting; Python programming language; basic Perl; R statistical programming language; basic html/CSS; Bioconductor bioinformatics programming tools; various advanced bioinformatics tools related to NGS, genomic and proteomics analysis.
Contribution to Bioinformatic Database/Tools
IntOGen system (www.intogen.org ; published in Nature Methods). Gitools (www.gitools.org).
Professional Organization Membership:
Keynote speaker/Invited talk/Trainer/Key resource person
Research Article (Published: 59, Accepted 1, Under review: 6, Total Impact Factor: ~ 360):
2018
66. Single cell RNA-sequencing reveals a metabolic aspect of apoptosis in Rbf mutant. Majd M Ariss, Abul B.M.M.K. Islam, Hayley Critcher, Maria Paula Zappia and Maxim V Frolov. (under review)
65. Mst. Noorjahan Begum, Suprovath Kumar Sarker, Golam Sarower Bhuyan, Md Tarikul Islam, Shahinur Haque, Tasnia Kawsar Konika, Syeda Kashfi Qadri, Tasnuva Ahmed, Hurjahan Banu, Nusrat Sultana, Asifuzzaman Rahat, Mohammad Amir Hossain, Kohinoor Jahan Shyamaly, Suraiya Begum, Sadia Sultana, Sheikh Maksudur Rahman, Narayan Saha, Taufiqur Rahman Bhuiyan, Mohiul Islam Chowdhury, Mizanul Hasan, M A Hasanat, Abu A. Sajib, Abul B.M.M.K Islam, Sharif Akhteruzzaman, Syed Saleheen Qadri, Firdausi Qadri and Kaiissar Mannoor. Profiling of carnitine and acylcarnitines of late-diagnosed hypothyroid patients with fatigue under levothyroxine treatment. (under review).
64. Suprovath Kumar Sarker, Md Tarikul Islam, Aparna Biswas, Golam Sarower Bhuyan, Rosy Sultana, Nusrat Sultana, Shagoofa Rakhshanda, Mst. Noorjahan Begum, Asifuzzaman Rahat, Sharmina Yeasmin, Mowshori Khannam, Asim Kumar Saha, Farjana Akther Noor, Abu A. Sajib, Abul Islam, Syeda Kashfi Qadri, Mohammod Shahidullah, Mohammad Abdul Mannan, AKM Muraduzzaman, Tahmina Shirin, Sheikh Maksudur Rahman, Syed Saleheen Qadri, Narayan Saha, Sharif Akhteruzzaman, Firdausi Qadri and Kaiissar Mannoor. ge-specific cut-off values of amino acids and acylcarnitines for diagnosis of inborn errors of metabolism using liquid chromatography tandem mass spectrometry. (under review)
63. Mst. Noorjahan Begum, Md Tarikul Islam, Sheikh Rezwan Hossain, Golam Sarower Bhuyan, Suprovath Kumar Sarker, Asifuzzaman Rahat, Shahinur Haque, Tasnia Kawsar Konika, Syeda Kashfi Qadri, Md. Sazzadul Islam, Rosy Sultana, Suraiya Begum, Sadia Sultana, Narayan Saha, Mizanul Hasan, MA Hasanat, Hurjahan Banu, Mohammad Halim, Hossain U. Shekhar, Emran Kabir Chowdhury, Abu A. Sajib, Abul Islam, Syed Saleheen Qadri, Sharif Akhteruzzaman, F. Qadri and Kaiissar Mannoor. Mutation spectrum in TPO gene of Bangladeshi patients with thyroid dyshormonogenesis and analysis of the effects of different mutations on the structural features and functions of TPO protein through in silico approach. (under review)
62. Maria Paula Zappia, Alice Rogers, Abul Islam and Maxim V Frolov. Rbf activates the myogenic transcriptional program to promote skeletal muscle differentiation. (under review)
62. Md. Wahid Murad, Salwa Mohd Mostafa and Abul B.M.M.K. Islam. A switch in bidirectional histone mark leads to differential modulation of lincRNAs involved in neuronal and hematopoietic cell differentiation from their progenitors. (under review)
61. Md. Sajedul Islam, Marwah Karim, Md. Wahid Murad and Abul B.M.M.K. Islam. In silico identified zika virus microRNAs aids in viral pathogenesis by targeting essential host genes involve in immune and neurological functions. BMC Infectious Disease. (accepted). [Impact Factor: 2.768]
60. Belen Lope.z-Millan, Rafael Diaz de la Guardia, Heleia Roca-Ho, Abul BMMK Islam, Eduardo Anguita, Damia Romero-Moya, Cristina Prieto, Francisco Gutierrez-Agüera, Jose Bejarano-Garcia, Jose Perez-Simon, Paula Costales, Fernando Anjos-Afonso, Montse Rovira, Pedro Marin, José Fuster, Alvaro Urbano-Ispizua, Clara Bueno, and Pablo Menendez. IMiDs mobilize Acute Myeloid Leukemia blasts to peripheral blood through downregulation of CXCR4 but do not potentiate AraC/Idarubicin activity in preclinical models of AML. Oncoimmunology, Volume 7, 2018 - Issue 9. [Impact Factor: 7.644]
2017
58. Atilla Biçer, Abul B.M.M.K. Islam, Serena Orlando, Edurne Gallastegui, Arnaud Besson, Rosa Aligué, Maria Jesús Pujol and Oriol Bachs. ChIP-Seq Analysis Identifies p27(Kip1)-Target Genes Involved in Cell Adhesion and Cell Signalling in Mouse Embryonic Fibroblasts. PLoS ONE. [Impact Factor: 2.806]
57. Ashok Amin and Abul B.M.M.K. Islam. Differential regulation of a tumor suppressor gene: MIG-6 in human Arthritis. American Journal of Arthritis Res.
56. Mandar Dave*, Abul B.M.M.K. Islam*, Roderick V. Jensen, Agueda Rostagno, Jorge Ghiso, Ashok R. Amin. Proteomic Analysis Shows Constitutive Secretion of MIF and p53-associated Activity of COX-2-/- Lung Fibroblasts. Genomic Proteomics and Bioinformatics (* equal contribution).
55. Mandar Dave, Abul B.M.M.K. Islam, Ashok R. Amin. The B-Box of HMGB1 amplifies nitric oxide production in human osteoarthritis-affected cartilage. American Journal of Arthritis Research.
54. Salwa Mohd. Mostafa, Md. Wahid Murad, Eusra Mohammad and Abul B.M.M.K. Islam. Intronic miRNA miR-3666 is a potential modulator of its host gene FOXP2 functions in neurodevelopment and may contribute to the pathogenesis of neurological disorders schizophrenia and autism. Journal of Applied Biotechnology & Bioengineering. 2017.
53. Anna Perearnau, Abul B.M.M.K. Islam, Edurne Gallastegui, Albert Jordan, Serena Orlando, Rosa Aligué, Maria Jesús Pujol and Oriol Bachs. p27Kip1, PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes. Nucleic Acid Research; 45 (9), 5086-5099. [Impact Factor: 9.202]
2016
52. Elizaveta Benevolenskaya, Abul B.M.M.K. Islam, Habibul Ahsan, Muhammad G. Kibriya, Farzana Jasmine, Ben Wolff, Umaima Al-Alem, Elizabeth Wiley, Andre Kajdacsy-Balla, Virgilia Macias, Garth H. Rauscher. DNA methylation and hormone receptor status in breast cancer. Clinical Epigenetics. 2016;8:17. Published: 16th February 2016. [impact factor: 4.543]
51. Refat Sharmin and Abul B.M.M.K. Islam. Conserved antigenic sites between MERS-CoV and Bat-coronavirus are revealed through sequence analysis. Source Code Biol Med. 2016 Mar 9;11:3
50. Jessica Segalés; Abul B.M.M.K. Islam; Roshan Kumar; Qi-Cai Liu; Pedro Sousa-Victor; F. Jeffrey Dilworth; Esteban Ballestar; Eusebio Perdiguero; Pura Munoz-Canoves. Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation. Skelet Muscle. 2016 Mar 15;6:9. [Impact Factor: 3.5]
49. Abul Islam, Mandar Dave, Sonia Amin; Roderick Jensen, Ashok Amin. Genomic, Lipidomic and Metabolomic Analysis of Cyclooxygenase-null Cells: Eicosanoid Storm, Cross Talk, and Compensation by COX-1. Genomics Proteomics Bioinformatics. 2016 Apr;14(2):81-93. [Impact Factor: 0.51]
48. Ashok R. Amin and Abul B.M.M.K Islam. Genomic Signaling in Human Osteoarthritis-Affected Chondrocytes by HMGB1: Induction of Pro-/Anti-Inflammatory and Matrix Depleting Activity. Journal of Molecular Signaling Updates. 2016; 1:11-23
47. Pablo Gómez-del Arco, Eusebio Perdiguero, Paula Sofia Yunes-Leites, Rebeca Acín-Pérez, Miriam Zeini, Antonio García-Gómez, Sreenivasan Krishnamoorthy, Miguel Jiménez-Alcázar, Jessica Segalés, Dolores López-Maderuelo, Beatriz Ornés, Luis Jesús Jiménez-Borreguero, Gaetano D´Amato, David Enshell-Seijffers, Bruce Morgan, Katia Georgopoulos, Abul B.M.M.K. Islam, Thomas Braun, José Luis de la Pompa, Johnny Kim, Jose Antonio Enríquez, Esteban Ballestar, Pura Muñoz-Cánoves, Juan Miguel Redondo. The Chromatin Remodelling Complex NuRD controls striated muscle identity and metabolic homeostasis. CELL Metabolism. 2016 May 10;23(5):881-92. [Impact Factor: 17.565]
46. Salwa Mohd. Mostafa and Abul B.M.M.K. Islam. An in silico approach predicted potential therapeutics that can confer protection from maximum pathogenic Hantaviruses. Future Virology. June 2016, 11:6(411-428). [Impact Factor: 1.011]
45. Shaily A. Amin and Abul B.M.M.K Islam. Diminished Genomics Signaling of Extravascular Coagulation and Fibrinolysis in Human Osteoarthritis (OA)-Affected Cartilage. Journal of Molecular Signaling Updates, 2016, 1:41-50
44. Alba Azagra, Lidia Román-González, Olga Collazo, Javier Rodríguez-Ubreva, Virginia de Yébenes, Burna Barneda-Zahonero, Jairo Rodríguez, Manuel de Moura, Joaquim Grego-Bessa, Irene Fernández-Duran, Abul B.M.M.K. Islam, Manel Esteller, Almudena Ramiro, Esteban Ballestar, and Maribel ParraIn vivo conditional deletion of HDAC7 reveals its requirement to establish proper B lymphocyte identity and development. Journal of Experimental Medicine. 2016. [Impact Factor: 11.240]
43. F Mateo, EJ Arenas, H Aguilar, J Serra-Musach, G Ruiz de Garibay, J Boni, M Maicas, S Du, F Iorio, C Herranz, A Islam, X Prado, A Llorente, A Petit, A Vidal, I Català, T Soler, G Venturas, A Rojo-Sebastian, H Serra, D Cuadras, I Blanco, J Lozano, F Canals, AM Sieuwerts, V de Weerd, MP Look, S Puertas, N García, AS Perkins, N Bonifaci, M Skowron, L Gómez-Baldó, V Hernández, A Martínez, M Martínez-Iniesta, X Serrat, J Cerón, J Brunet, MP Barretina, M Gil, C Falo, A Fernández, I Morilla, S Pernas, MJ Plà, X Andreu, MA Seguí, R Ballester, E Castellà, M Nellist, S Morales, J Valls, A Velasco, X Matias-Guiu, A Figueras, J Vicente Sánchez-Mut, M Sánchez-Céspedes, A Cordero, J Gómez-Miragaya, L Palomero, A Gómez, TF Gajewski, EEW Cohen, M Jesiotr, L Bodnar, M Quintela-Fandino, N López-Bigas, R Valdés-Mas, XS Puente, F Viñals, O Casanovas, M Graupera, J Hernández-Losa, S Ramón y Cajal, L García-Alonso, J Saez-Rodriguez, M Esteller, A Sierra, N Martín-Martín, A Matheu, A Carracedo, E González-Suárez, M Nanjundan, J Cortés, C Lázaro, MD Odero, JWM Martens, G Moreno-Bueno, MH Barcellos-Hoff, A Villanueva, RR Gomis and MA Pujana. Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition. Oncogene. 19 December 2016; doi: 10.1038/onc.2016.427. [Impact Factor: 7.932]
2015
42. Chiara Di Vona, Daniela Bezdan, Abul B.M.M.K. Islam, Eulàlia Salichs, Nuria López-Bigas, Stephan Ossowski, and Susana de la Luna. Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase. Molecular CELL [Impact Factor: 14.464]
41. Renáta Váraljai*, Abul B.M.M.K. Islam*, Michael L. Beshiri, Jalees Rehman, Nuria Lopez-Bigas and Elizaveta V. Benevolenskaya. Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells. [* equal contribution]. Genes and Development [Impact Factor:12.64]
40. Leonor Gama-Norton, Eva Ferrando, Cristina Ruiz-Herguido, Zhenyi Liu, Jordi Guiu, Abul B. M. M. K. Islam, Sung-Uk Lee, Minhong Yan, Cynthia J. Guidos, Nuria López-Bigas, Takahiro Maeda, Lluis Espinosa, Raphael Kopan & Anna Bigas. Notch signal strength controls cell fate in the haemogenic endothelium. Nature Communication [Impact Factor: 11.47]
39. Bruna Barneda-Zahonero, Olga Collazo, Irene Fernández-Duran, Jordi Serra-Musach, Alba Azagra, Abul B.M.M.K. Islam, Antonio Gómez, Lidia Román-González, August Vidal, Nuria Lopez-Bigas, Alberto Villanueva, Manel Esteller, Maribel Parra. HDAC7 is underexpressed in particular types of leukemia and lymphoma and its expression induces apoptosis and c-Myc downregulation. Cell Death & Disease. [Impact Factor: 5.177]
38. Mary Truscott, Abul B.M.M.K. Islam and Maxim V. Frolov. Novel regulation and functional interaction of polycistronic miRNAs. RNA. [Impact Factor: 4.622]
37. Daniel Cuadras, Xianshu Wang, Daniel Barrowdale, Gorka Ruiz de Garibay, Pablo Librado, Alejando Sánchez-Gracia, Julio Rozas, Núria Bonifaci, Lesley McGuffog, Vernon Pankratz, Abul B.M.M.K. Islam, ........... et al. and Miguel Angel Pujana. Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers. PLoS ONE [Impact Factor: 3.53]
36. Modhusudan Shaha, Mohammad Ariful Islam, Abul B.M.M.K. Islam, Firoz Ahmed, Md. Majibur Rahman, Sabita Rezawana Rahman. Prediction of new conserved epitopes in protein 3D model to neutralize Influenza A virus strain H3N3 circulating in Bangladesh. International Journal of Current Research in Chemistry and Pharmaceutical Sciences.
2014
35. Lluís Millán-Ariño, Abul B.M.M.K. Islam, Andrea Izquierdo-Bouldstridge, Regina Mayor, Jean-Michel Terme, Neus Luque, Mónica Sancho, Núria López-Bigas and Albert Jordan. Mapping of six somatic linker histone H1 variants in human breast cancer cells uncovers specific features of H1.2. Nucleic Acids Research. [Impact Factor: 8.278]
34. Ashok R. Amin and Abul B.M.M.K Islam. Genomic Analysis and Differential Expression of HMG and S100A Family in Human Arthritis: Upregulated Expression of Chemokines, IL-8 and Nitric Oxide by HMGB1. DNA and Cell Biology. [Impact Factor: 2.344].
33. Helena Aguilar, Ander Urruticoechea, Pasi Halonen, Kazuma Kiyotani, Taisei Mushiroda, Xavier Barril, Jordi Serra-Musach1, Abul B.M.M.K. Islam, Livia Caizzi, Luciano Di Croce, Ekaterina Nevedomskaya, Wilbert Zwart, Josefine Bostner, Elin Karlsson, Gizeh Pérez Tenorio, Tommy Fornander, Dennis C. Sgroi, Rafael Garcia-Mata, Maurice P.H.M. Jansen, Nadia García, Núria Bonifaci, Fina Climent, María Teresa Soler, Alejo Rodríguez-Vida, Miguel Gil, Joan Brunet, Griselda Martrat, Laia Gómez-Baldó, Ana I. Extremera, Agnes Figueras, Josep Balart, Robert Clarke, Kerry L. Burnstein, Kathryn E. Carlson, John A. Katzenellenbogen, Miguel Vizoso, Manel Esteller, Alberto Villanueva, Ana B. Rodríguez-Peña, Xosé R. Bustelo, Yusuke Nakamura, Hitoshi Zembutsu, Olle Stål, Roderick L. Beijersbergen and Miguel Angel Pujana. VAV3 mediates resistance to breast cancer endocrine therapy. Accepted: Breast Cancer Research. [Impact Factor: 5.87]
32. Mary Truscott, Abul B.M.M.K. Islam, James Lightfoot, Núria López-Bigas and Maxim V. Frolov. An intronic microRNA links Rb/E2F and EGFR signaling. PLoS Genetics. [Impact Factor: 8.517]
31. Refat Sharmin and Abul B.M.M.K. Islam. A highly conserved YPKCDRA epitope in the RNA directed RNA polymerase of human coronaviruses can be used as epitope-based universal vaccine design. BMC Bioinformatics [IF: 3.02]
30. Md. Ashraful Islam Bhuiya and Abul B.M.M.K. Islam. Bioinformatics analysis identified distinct features between stress and non-stress related genes of different plants. Enliven:Bioinformatics.
29. Jordi Guiu, Dylan J.M. Bergen, Emma De Pater, Abul B.M.M.K Islam, Verónica Ayllón, leonor Gama-Norton, Cristina Ruiz-Herguido, Jessica González, Nuria López-Bigas, Pablo Menéndez, lluis espinosa, Anna Bigas. Identification of CDCA7 as a novel Notch transcriptional target involved in Hematopoietic Stem Cells emergence. (Journal of Experimental Medicine) [Impact Factor: 13.912].
28. Roser Vento-Tormo, Javier Rodríguez-Ubreva, Lorena Di Lisio, Abul B. M. M. K. Islam, Jose M. Urquiza, Henar Hernando, Nuria López-Bigas, Claire Shannon-Lowe, Nerea Martínez, Santiago Montes-Moreno, Miguel A. Piris and Esteban Ballestan. NF-kB directly mediates epigenetic deregulation of common microRNAs in Epstein-Barr virus-mediated transformation of B-cells and in lymphomas. Nucleic Acids Research. [Impact Factor: 8.278]
2013
27. Mulero C, Ferres-Marco D, Abul B.M.M.K. Islam, Pecoraro M , Charneco C, Bellora N, Toll A, Gallardo F, Asensio E, López-Arribillaga E, Rodilla V, Iglesias M, Shih V, Alba M, Di Croce L, Hoffmann A, Villà-Freixa J, López-Bigas N, Keyes B, Domínguez M, Bigas A and Espinosa L. Chromatin-Bound IκBα Regulates a Subset of Polycomb Target Genes in Differentiation and Cancer. July 11, 2013. Cancer CELL. [Impact Factor: 28.2]
26. Aaron M Ambrus, Abul BMMK Islam, Katherine B. Holmes, Richard Suckling, Nam Sung Moon, Elizaveta V Benevolenskaya, Nuria Lopez-Bigas and Maxim V Frolov. Loss of E2F compromises mitochondrial function and protects cells from irradiation-induced apoptosis in Drosophila. Developmental CELL. [IF: 14.091]
25. Hernando H, Shannon-Lowe C, Abul B.M.M.K. Islam, Fatima Al-Shahrour, Javier Rodríguez-Ubreva, Virginia C. Rodríguez-Cortez, Biola M. Javierre, Cristina Mangas, Agustin F. Fernandez, Maribel Parra, Henry-Jacques Delecluse, Manel Esteller, Eduardo Lopez-Granados, Mario F. Fraga, Nuria Lopez-Bigas, and Esteban Ballestar. Hypomethylation of B cell specific genes during conversion of resting B cells to proliferating lymphoblasts is an early event in lymphomagenesis. 2013, 14:R3 . Genome Biology. [IF: 10.3]
24. Lorenzo de la Rica, Mireia García, Javier Rodríguez-Ubreva, Abul BMMK Islam, Jose M Urquiza, Henar Hernando, Jesper Christensen, Kristian Helin, Carmen Gómez-Vaquero and Esteban Ballestar. PU.1 targets Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiation.Genome Biology. [IF: 10.3]
23. Román-González L, Barneda-Zahonero B, Collazo O, Rafati H, Abul B.M.M.K. Islam, Thomas Graf, Núria López-Bigas, Tokameh Mahmoudi and Maribel Parra. Downregulation of HDAC7, an essential repressor of myeloid-inappropriate genes in B cells is required for transdifferentiation into macrophages. 2013 May; 9(5):e1003503. PLoS Genetics. [IF: 8.6]
22. Henar Hernando, Abul B. M. M. K. Islam, Javier Rodriguez-Ubreva, Claire Shannon-Lowe, Nuria Lopez-Bigas and Esteban Balle. Epstein Barr Virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation. Nucleic Acid Research. [IF: 8.278]
21. Mercedes Herrera, Abul B.M.M.K. Islam, Alberto Herrera, Paloma Martín, Ignacio Casal, Antonio García de Herreros5, Félix Bonilla1, Cristina Peña. Heterogeneity of cancer-associated fibroblast from human colon tumor shows specific prognostic gene expre expression signature. Clinical Cancer Research. [IF: 7.837]
20. Lorenzo de la Rica, José M Urquiza, David Gómez-Cabrero, Abul B. M. M. K. Islam, Nuria López-Bigas, Jesper Tegnér, René E.M. Toes, and Esteban Ballestar. Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression. 2013 Mar;41:6-16. Journal of Autoimmunity [IF: 7.37]
2012
19. Beshiri M, Holmes K, Richter W, Hess S, Abul B.M.M.K. Islam, Yan Q, Plante L, Gévry N, Lopez-Bigas K, Kaelin W and Benevolenskaya E. Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation. (PNAS Nov 6, 2012, 109 (45) 18499-18504). PNAS. [IF: 9.68]
18. Bayarmagnai B, Nicolay B, Abul B.M.M.K. Islam, Lopez-Bigas N and Frolov M. Drosophila GAGA Factor is required for full activation of the dE2F1-Yki/Sd transcriptional program. (2012 Nov 15;11(22):4191-202). Cell Cycle. [IF: 4.999]
2011
17. Abul B.M.M.K. Islam, Richter W, Lopez-Bigas N, Benevolenskaya, EV. Selective targeting of histone methylation. Cell Cycle (IF; 4.999)
16. Abul B.M.M.K. Islam, Richter WF, Jacobs LA, Lopez-Bigas N and Benevolenskaya EV Coregulation of Histone-modifying Enzymes in Cancer. PLoS One (IF: 4.61)
15. Truscott M, Abul B.M.M.K. Islam, Lopez-Bigas N and Frolov MV mir-11 limits the proapoptotic function of its host gene, dE2f1. Genes and Development (IF: 14.198).
14. Nicolay B, Bayarmagnai B*, Abul B.M.M.K. Islam*, Lopez-Bigas N and Frolov MV. Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit. Genes & Development (IF:14.198). (* equal contribution)
2010
13. Beshiri ML, Abul B.M.M.K. Islam, DeWaal DC, Richter WF, Love J, Lopez-Bigas N, Benevolenskaya EV. Genome-wide Analysis using ChIP to Identify Isoform-specific Gene Targets. JoVE (IF 1.19; >15,000 visit to video protocol)
12. Ferreiro I, Joaquin M, Abul B.M.M.K. Islam, Gonzalo Gomez, Montserrat Barragan, Luis Lombardia, Orlando Dominguez, David G. Pisano, Nuria Lopez-Bigas, Angel R. Nebreda and Francesc Posas. Whole genome analysis of p38 SAPK-mediated gene expression upon stress. BMC Genomics, (IF: 4.07)
11. Aguilar H, Sole X, Bonifaci N, Serra-Musach J, Abul B.M.M.K. Islam, Lopez-Bigas N, Méndez-Pertuz M, Beijersbergen RL, Lázaro C, Urruticoechea A, Pujana MA. Biological reprogramming in acquired resistance to endocrine therapy of breast cancer. Oncogene. (IF: 6.373).
10. Gundem G, Perez-Llamas C, Jene-Sanz A, Kedzierska A, Abul B.M.M.K. Islam, Deu-Pons J, Furney S and Lopez-Bigas N. IntOGen: Integration and data-mining of multidimensional oncogenomic data. Nature Methods(IF:19.276) .
2009-2004
9. Shuvra Kanti Dey, Hideaki Shimizu, Tung Gia Phan, Yuko Hayakawa, Abul Islam, Abul Faiz Mohammad Salim, Anisur Rahman Khan, Masashi Mizuguchi, Shoko Okitsu, Hiroshi Ushijima. Molecular epidemiology of adenovirus infection among infants and children with acute gastroenteritis in Dhaka City, Bangladesh. 2009. Infection, Genetics and Evolution. (IF: 3.128)
8. Saeid Abroun, Ken-ichiro Otsuyama, Karim Shamsasenjan, Abul Islam, Jakia Amin, Michio M Kawano. Galectin-1 supports the survival of CD45RA(-) primary myeloma cells in vitro. 2008. British Journal of Hematology. (2008 Sep;142(5):754-65. ). (IF: 4.941).
7. Shuvra Kanti Dey, Abul Islam, Masashi Mizuguchi, Shoko Okitsu, Hiroshi Ushijima. Epidemiological and molecular analysis of astrovirus gastroenteritis in Dhaka City, Bangladesh. Journal of Tropical Pediatrics. Dec 2008 (IF: 1.388)
6. Khademul Islam, Md. Ibrahim Khalil, Chowdhury Rafiqul Ahsan and Mahmuda Yasmin and Jamalun Nessa. 2007. Analysis of immue responses against Helicobacter pylori in rabbit. World J of Gastroenterology; 13(4):600-606. (IF: 2.092)
5. Md. Shahidul Islam, ABM Md. Khademul Islam, Chowdhury Rafiqul Ahsan, Mahmuda Yasmin and Jamalun Nessa. 2006. Seroprevalence of Helicabacter pylori Among Underprivileged Bangladeshi Children: Case Study in a Day-care Center. Bangladesh Journal of Microbiology, 23(1): 24-28.
4. Farhana Rahman, ABM Md. Khademul Islam, Jamalun Nessa, Chowdhury Rafiqul Ahsan and Mahmuda Yasmin. 2005. Correlation in Prevalence, Risk Factors and Serological Detection of Helicobacter pylori by Different Techniques. Bangladesh Journal of Microbiology, 22(2):152-157.
3. ABM Md. Khademul Islam, Mahmuda Yasmin, Jamalun Nessa, Chowdhury Rafiqul Ahsan. 2005. Helicobacter pylori infection in Bangladeshi population: Serodiagnosis, Seroprevalence and Risk factors. The Dhaka University J. of Biological Sciences. 14(1):1-8.
2. Jakia Amin, Abul Bashar Mir Md. Khademul Islam and Md. Majibur Rahman.2004. Prevalence and antibiotic resistance of pathogenic microorganisms of poultry products and associated manpower. Bangladesh Journal of Microbiology. 21(2):101-103.
1. ABM Md. Khademul Islam, Jamalun Nessa, Mahmuda Yasmin, Chowdhury Rafiqul Ahsan. 2002. Seroprevalence of S. flexneri 2a infection in Bangladeshi population and analysis of its relationship with sex, age, blood group, acidity. Bangladesh Journal of Microbiology, 19(1 & 2): 73-77.
Fundamentals of Genetic Engineering & Biotechnology
Physiology & Biochemistry of living organisms-I
Virology
Biochemistry & Molecular Biology of Diseases
Biotechnology of Microbial Systems
Genomics Proteomics Bioinformatics
Computational Genomics and Systems Biology
Seminar presentation
Physiology-I/II (Human)
Bioinformatics
Genomics
Molecular Biology and Biotechnology
Immunopharmacology
Pharmaceutical Biotechnology
Statistics and Bioinformatics
Marine Biotechnology & Therapeutics
Practical/Lab experiments
Bachelor Research Projects:
Master thesis:
MPhil/PhD:
Medical Biotechnology (Genomics & Molecular Biology of Disease): Epigenetic, Genetic and Immunologic mechanisms of human diseases, specially cancer, arthritis, diabetes and metabolic disorders; and bacterial pathogenesis. Epigenetic drug target and drug discovery. Mechanism and drug/vaccine discovery against infectious disease.
Bioinformatics, Computational and Systems Biology: In Silico/computer aided drug design (CADD); Vaccine design. Optimization, analysis and management of Next Generation (NGS)/Third generation sequence data (whole genome sequencing, exonm seq, ChIPseq, RNAseq, Single Cell RNAseq, MethylomeSeq etc), HiC, microarray, Chip-on-chip, ChIP-tiling and other high-throughput genomic and proteomic data; Data integration, mining and visualization; bioinformatic study of Epigenetic mechanisms in cancer; drug target identification, biological PPIN/GRN/PCN/metabolic network; MALDI/NMR etc proteomic data analysis for marker identification for cancer diagnosis; prediction of structure based regulatory elements in genomics and proteomic data; Metagenomics;
Fundamentals of Genetic Engineering & Biotechnology
Physiology & Biochemistry of living organisms-I
Virology
Biochemistry & Molecular Biology of Diseases
Biotechnology of Microbial Systems
Genomics Proteomics Bioinformatics
Computational Genomics and Systems Biology
Seminar presentation
Physiology-I/II (Human)
Bioinformatics
Genomics
Molecular Biology and Biotechnology
Immunopharmacology
Pharmaceutical Biotechnology
Statistics and Bioinformatics
Marine Biotechnology & Therapeutics
Practical/Lab experiments
Bachelor Research Projects:
Master thesis:
MPhil/PhD:
Present position: